| Title |
The Need for Randomization in Animal Trials: An Overview of Systematic Reviews
|
|---|---|
| Published in |
PLOS ONE, June 2014
|
| DOI | 10.1371/journal.pone.0098856 |
| Pubmed ID | |
| Authors |
Jennifer A Hirst, Jeremy Howick, Jeffrey K Aronson, Nia Roberts, Rafael Perera, Constantinos Koshiaris, Carl Heneghan |
| Abstract |
Randomization, allocation concealment, and blind outcome assessment have been shown to reduce bias in human studies. Authors from the Collaborative Approach to Meta Analysis and Review of Animal Data from Experimental Studies (CAMARADES) collaboration recently found that these features protect against bias in animal stroke studies. We extended the scope the work from CAMARADES to include investigations of treatments for any condition. |
X Demographics
The data shown below were collected from the profiles of 78 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 26 | 33% |
| Australia | 3 | 4% |
| Spain | 3 | 4% |
| United States | 3 | 4% |
| Netherlands | 2 | 3% |
| Belgium | 2 | 3% |
| Canada | 2 | 3% |
| Hong Kong | 1 | 1% |
| France | 1 | 1% |
| Other | 8 | 10% |
| Unknown | 27 | 35% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 46 | 59% |
| Scientists | 21 | 27% |
| Practitioners (doctors, other healthcare professionals) | 8 | 10% |
| Science communicators (journalists, bloggers, editors) | 3 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 209 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | <1% |
| United Kingdom | 2 | <1% |
| United States | 2 | <1% |
| Spain | 1 | <1% |
| Chile | 1 | <1% |
| Unknown | 201 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 34 | 16% |
| Researcher | 31 | 15% |
| Student > Bachelor | 26 | 12% |
| Student > Master | 24 | 11% |
| Student > Doctoral Student | 12 | 6% |
| Other | 37 | 18% |
| Unknown | 45 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 48 | 23% |
| Agricultural and Biological Sciences | 30 | 14% |
| Neuroscience | 15 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 15 | 7% |
| Nursing and Health Professions | 10 | 5% |
| Other | 38 | 18% |
| Unknown | 53 | 25% |