This study found that animal studies that were not randomized reported larger effect sizes: https://t.co/6c9paAZP9K
and 35% blinding outcome assessments https://t.co/kjnyiDC3xX. Never mind the appropriateness of the statistical analysis, which is often too poorly reported to assess. Almost none that I read are preregistered or publish data.
@siminevazire I sign my reviews - if suggesting a relevant paper of ours I say clearly that citation is not a condition for a positive review, and if they can find a different source they could use that. Also suggested 2ndry aanalyses of our published data
I perform #RCTs, no experience with #animalresearch. Not randomizing and not blinding during treatment allocation and data analysis does seem like a serious issue also in #animalstudies, see https://t.co/8Hh4XL0sys & https://t.co/cIJbXQigx1 (3/4)
@Maratosflier Some discussion of the idea: https://t.co/twsKbJ6XLu
Randomization, allocation concealment, blinding in animal studies https://t.co/twsKbJ6XLu
@bigfatsurprise And in animal research, where blinding is possible, it is seldom done: http://t.co/EvRYriN6hU
PLOS ONE: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/qdcxX1r1WH
Animal trials are not exempt from the biases faced in human trials: http://t.co/F8grcAc6rF - need to randomize, conceal allocation, blind ax
The Need for Randomization in Animal Trials: An Overview of Systematic Reviews. http://t.co/oQBH0b5p3M
#ad #ebm The need for randomization in animal trials: an overview of systematic reviews... http://t.co/7wWCmTXs3O http://t.co/m3IVtCAMiH
#PLOSONE study demonstrates that randomisation impacts on experimental science regardless of disease model http://t.co/Ui3KA7mbrD
#PLOSONE study demonstrates that randomisation impacts on experimental science regardless of disease model http://t.co/Ui3KA7mbrD
#PLOSONE "unduly biased animal studies should not be allowed to constitute part of the rationale for human trials" http://t.co/Ui3KA7mbrD
#PLOSONE study demonstrates that randomisation impacts on experimental science regardless of disease model http://t.co/Ui3KA7mbrD
Another sobering overview of the methodological quality of animal research http://t.co/r2lftbNJDR
Randomization needed in animal trials. Great paper by a fellow Canadian @JeremyHowick @UniofOxford http://t.co/YZ7M7ISuY5
Randomization needed in animal trials. Great paper by a fellow Canadian @JeremyHowick @UniofOxford http://t.co/YZ7M7ISuY5
Randomization needed in animal trials. Great paper by a fellow Canadian @JeremyHowick @UniofOxford http://t.co/YZ7M7ISuY5
MT @vmontori @iainchalmersTTi Another sobering overview of methodological quality of animal research http://www.http://t.co/eWJaB2BYrF
Another sobering overview of the methodological quality of animal research http://t.co/r2lftbNJDR
Another sobering overview of the methodological quality of animal research http://t.co/r2lftbNJDR
Another sobering overview of the methodological quality of animal research http://t.co/r2lftbNJDR
The Need for Randomization in Animal Trials: Overview of Systematic Reviews http://t.co/fTcWyGpBqO - @PLOSONE MT @xgu2
Rt @iainchalmersTTi Another sobering overview of the methodological quality of animal research @SENC_ http://t.co/jTKWOXZcnY
Another sobering overview of the methodological quality of animal research http://t.co/r2lftbNJDR
Another sobering overview of the methodological quality of animal research http://t.co/r2lftbNJDR
@plosmedicine - Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/yXmyB0jjhm - #publichealth
Another sobering overview of the methodological quality of animal research http://t.co/r2lftbNJDR
Another sobering overview of the methodological quality of animal research http://t.co/r2lftbNJDR
#wasteinresearch RT @SABREresearchUK: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/vNg0hFMXFA
#wasteinresearch RT @SABREresearchUK: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/vNg0hFMXFA
Whoops. RT @AMCELL: Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/kCYzn9jClh
Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/if1OS3SUyW
Further evidence for the importance of randomisation and blinding in animal studies #ARRIVEguidelines http://t.co/TcRhdMQK72
Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/if1OS3SUyW
The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/qYKmeQIJgU
The need for randomisation in animal studies http://t.co/OZ6KyBeij7
The need for randomisation in animal studies http://t.co/OZ6KyBeij7
【無作為化されていない動物実験では無作為化試験に比べ効果が有意に大。評価項目が主観的な場合,盲検化の有無も影響:総説31報解析】 Plos One http://t.co/iLkHYNZjIQ
The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/qYKmeQIJgU
The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/qYKmeQIJgU
The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/qYKmeQIJgU
The need for randomization, allocation concealment, and blind outcome assessment in animal research http://t.co/ziFb8Egrgr
The N eed for randomization, allocation concealment, and blind outcome assessment in animal research http://t.co/ziFb8Egrgr
The need for randomisation in animal studies http://t.co/OZ6KyBeij7
The need for randomisation in animal studies http://t.co/OZ6KyBeij7
The need for randomisation in animal studies http://t.co/OZ6KyBeij7
The need for randomisation in animal studies http://t.co/OZ6KyBeij7
The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/qYKmeQIJgU
The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/qYKmeQIJgU
The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/qYKmeQIJgU
The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/5aF8PCFeON
#PLOSONE: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews #3Rs http://t.co/Yj7KQC4sbK
#PLOSONE: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews #3Rs http://t.co/Yj7KQC4sbK
#PLOSONE: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews #3Rs http://t.co/Yj7KQC4sbK
Animal research needs randomization, allocation concealment & blind outcome assessment say @cebmblog & @JeremyHowick http://t.co/ohearR2OYw
#wasteinresearch RT @SABREresearchUK: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/vNg0hFMXFA
#wasteinresearch RT @SABREresearchUK: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/vNg0hFMXFA
Animal research needs randomization, allocation concealment & blind outcome assessment say @cebmblog & @JeremyHowick http://t.co/ohearR2OYw
#PLOSONE: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/Ie264YwM7H #3Rs #STEM #HE
#PLOSONE: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/Ie264YwM7H #3Rs #STEM #HE
http://t.co/u3twakNMzv Randomization 4 animal trials 2!
La necesidad de aleatorizar a los animales en los estudios de ciencia básicos. Revisión sistemática. http://t.co/YVbQ9bYniN
The need for randomization in animal trials. Overview of systematic reviews. Randomization for all, humans & animals. http://t.co/YVbQ9bYniN
Animal research needs randomization, allocation concealment & blind outcome assessment say @cebmblog & @JeremyHowick http://t.co/ohearR2OYw
Animal research needs randomization, allocation concealment & blind outcome assessment say @cebmblog & @JeremyHowick http://t.co/ohearR2OYw
Animal research needs randomization, allocation concealment & blind outcome assessment say @cebmblog & @JeremyHowick http://t.co/ohearR2OYw
"unduly biased animal studies should not be allowed to constitute part of the rationale for human trials..." http://t.co/YT8PT13t3S
"unduly biased animal studies should not be allowed to constitute part of the rationale for human trials..." http://t.co/YT8PT13t3S
"unduly biased animal studies should not be allowed to constitute part of the rationale for human trials..." http://t.co/YT8PT13t3S
"unduly biased animal studies should not be allowed to constitute part of the rationale for human trials..." http://t.co/YT8PT13t3S
"unduly biased animal studies should not be allowed to constitute part of the rationale for human trials..." http://t.co/YT8PT13t3S
"unduly biased animal studies should not be allowed to constitute part of the rationale for human trials..." http://t.co/YT8PT13t3S
"unduly biased animal studies should not be allowed to constitute part of the rationale for human trials..." http://t.co/YT8PT13t3S
Many human trials based on animal studies yet most animal studies biased: http://t.co/2vlkmFmuKd
RT @SABREresearchUK: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/FGYsPsvbL3
#wasteinresearch RT @SABREresearchUK: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/vNg0hFMXFA
RT @SABREresearchUK: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/nSlTREcmcn
#wasteinresearch RT @SABREresearchUK: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/vNg0hFMXFA
@PaulGlasziou Should ARRIVE more aggressively promote bias control? MT The Need for Randomization in Animal Trials http://t.co/WplaKcRwUW
#wasteinresearch RT @SABREresearchUK: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/vNg0hFMXFA
#wasteinresearch RT @SABREresearchUK: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/vNg0hFMXFA
MT @PaulGlasziou @SABREresearchUK: The Need for Randomization in Animal Trials http://t.co/RkDekZmCh0 Wasted $€£ in due diligence for drigs
#wasteinresearch RT @SABREresearchUK: The Need for Randomization in Animal Trials: An Overview of Systematic Reviews http://t.co/vNg0hFMXFA