| Title |
Recapitulation of Tumor Heterogeneity and Molecular Signatures in a 3D Brain Cancer Model with Decreased Sensitivity to Histone Deacetylase Inhibition
|
|---|---|
| Published in |
PLOS ONE, December 2012
|
| DOI | 10.1371/journal.pone.0052335 |
| Pubmed ID | |
| Authors |
Stuart J. Smith, Martin Wilson, Jennifer H. Ward, Cheryl V. Rahman, Andrew C. Peet, Donald C. Macarthur, Felicity R. A. J. Rose, Richard G. Grundy, Ruman Rahman |
| Abstract |
Physiologically relevant pre-clinical ex vivo models recapitulating CNS tumor micro-environmental complexity will aid development of biologically-targeted agents. We present comprehensive characterization of tumor aggregates generated using the 3D Rotary Cell Culture System (RCCS). |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 128 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 35 | 27% |
| Researcher | 23 | 18% |
| Student > Master | 15 | 12% |
| Student > Bachelor | 10 | 8% |
| Student > Doctoral Student | 10 | 8% |
| Other | 13 | 10% |
| Unknown | 23 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 27 | 21% |
| Biochemistry, Genetics and Molecular Biology | 24 | 19% |
| Medicine and Dentistry | 20 | 16% |
| Engineering | 10 | 8% |
| Neuroscience | 4 | 3% |
| Other | 18 | 14% |
| Unknown | 26 | 20% |