Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11814645-B2 United States of America 14 Nov 2023
Antigen binding receptors specific for mutated Fc domains Grant US-11679127-B2 United States of America 20 Jun 2023
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11674159-B2 United States of America 13 Jun 2023
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11634730-B2 United States of America 25 Apr 2023
2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF… Application WO-2023031683-A1 World Intellectual Property Organisation (WIPO) 09 Mar 2023
Systems, methods and compositions for sequence manipulation with optimized functional… Grant US-11597919-B2 United States of America 07 Mar 2023
Compositions and methods of use of CRISPR-Cas systems in nucleotide repeat disorders Grant US-11591581-B2 United States of America 28 Feb 2023
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11549127-B2 United States of America 10 Jan 2023
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11479794-B2 United States of America 25 Oct 2022
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11473108-B2 United States of America 18 Oct 2022
Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for… Grant US-11407985-B2 United States of America 09 Aug 2022
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11401532-B2 United States of America 02 Aug 2022
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11332761-B2 United States of America 17 May 2022
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11293034-B2 United States of America 05 Apr 2022
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11274318-B2 United States of America 15 Mar 2022
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11242543-B2 United States of America 08 Feb 2022
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11186849-B2 United States of America 30 Nov 2021
CRISPR-Cas systems, crystal structure and uses thereof Grant US-11155795-B2 United States of America 26 Oct 2021
Delivery, engineering and optimization of systems, methods and compositions for sequence… Grant US-11041173-B2 United States of America 22 Jun 2021
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11028412-B2 United States of America 08 Jun 2021
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11008590-B2 United States of America 18 May 2021
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11008589-B2 United States of America 18 May 2021
Delivery, engineering and optimization of tandem guide systems, methods and compositions… Grant US-11008588-B2 United States of America 18 May 2021
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-11001863-B2 United States of America 11 May 2021
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10988782-B2 United States of America 27 Apr 2021
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10988780-B2 United States of America 27 Apr 2021
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10982230-B2 United States of America 20 Apr 2021
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10982231-B2 United States of America 20 Apr 2021
Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for… Grant US-10946108-B2 United States of America 16 Mar 2021
USE OF PYRVINIUM FOR THE TREATMENT OF A RAS PATHWAY MUTATED ACUTE MYELOID LEUKEMIA Application WO-2021043724-A1 World Intellectual Property Organisation (WIPO) 11 Mar 2021
Methods, models, systems, and apparatus for identifying target sequences for Cas enzymes… Grant US-10930367-B2 United States of America 23 Feb 2021
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10900054-B2 United States of America 26 Jan 2021
Compositions and methods of use of CRISPR-Cas systems in nucleotide repeat disorders Grant US-10851357-B2 United States of America 01 Dec 2020
CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION Grant EP-3252160-B1 European Patent Office 28 Oct 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10793878-B1 United States of America 06 Oct 2020
DELIVERY AND USE OF THE CRISPR-CAS SYSTEMS, VECTORS AND COMPOSITIONS FOR HEPATIC… Grant EP-3011031-B1 European Patent Office 30 Sep 2020
Functional genomics using CRISPR-Cas systems, compositions, methods, screens and… Grant US-10781444-B2 United States of America 22 Sep 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10774344-B1 United States of America 15 Sep 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10752920-B2 United States of America 25 Aug 2020
Optimized CRISPR-Cas double nickase systems, methods and compositions for sequence… Grant US-10711285-B2 United States of America 14 Jul 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10676759-B2 United States of America 09 Jun 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10669560-B2 United States of America 02 Jun 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10640791-B2 United States of America 05 May 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10626419-B2 United States of America 21 Apr 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10612045-B2 United States of America 07 Apr 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10597680-B2 United States of America 24 Mar 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10577631-B2 United States of America 03 Mar 2020
Delivery and use of the CRISPR-Cas systems, vectors and compositions for hepatic… Grant US-10577630-B2 United States of America 03 Mar 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10570419-B2 United States of America 25 Feb 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10563227-B2 United States of America 18 Feb 2020
Systems, methods and compositions for sequence manipulation with optimized functional… Grant US-10550372-B2 United States of America 04 Feb 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10550407-B2 United States of America 04 Feb 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10533190-B2 United States of America 14 Jan 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10526619-B2 United States of America 07 Jan 2020
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10519467-B2 United States of America 31 Dec 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10513712-B2 United States of America 24 Dec 2019
Crispr enzyme mutations reducing off-target effects Grant US-10494621-B2 United States of America 03 Dec 2019
CRISPR-BASED GENOME MODIFICATION AND REGULATION Grant EP-3363902-B1 European Patent Office 27 Nov 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10487341-B2 United States of America 26 Nov 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10443076-B2 United States of America 15 Oct 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10428352-B2 United States of America 01 Oct 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10421980-B2 United States of America 24 Sep 2019
INDUCIBLE DNA BINDING PROTEINS AND GENOME PERTURBATION TOOLS AND APPLICATIONS THEREOF Grant EP-3494997-B1 European Patent Office 18 Sep 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10415061-B2 United States of America 17 Sep 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10407697-B2 United States of America 10 Sep 2019
Methods and compositions or RNA-directed target DNA modification and for RNA-directed… Grant US-10400253-B2 United States of America 03 Sep 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10385360-B2 United States of America 20 Aug 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10358659-B2 United States of America 23 Jul 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10358658-B2 United States of America 23 Jul 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10351878-B2 United States of America 16 Jul 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10337029-B2 United States of America 02 Jul 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10308961-B2 United States of America 04 Jun 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10301651-B2 United States of America 28 May 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10266850-B2 United States of America 23 Apr 2019
Engineering of systems, methods and optimized guide compositions for sequence manipulation Grant EP-2940140-B1 European Patent Office 27 Mar 2019
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10227611-B2 United States of America 12 Mar 2019
CRISPR-BASED GENOME MODIFICATION AND REGULATION Grant EP-3138911-B1 European Patent Office 05 Dec 2018
CRISPR-BASED GENOME MODIFICATION AND REGULATION Grant EP-3138912-B1 European Patent Office 05 Dec 2018
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10113167-B2 United States of America 30 Oct 2018
Methods and compositions for RNA-directed target DNA modification and for RNA-directed… Grant US-10000772-B2 United States of America 19 Jun 2018
CRISPR-Cas component systems, methods and compositions for sequence manipulation Grant US-9840713-B2 United States of America 12 Dec 2017
CRISPR-Cas component systems, methods and compositions for sequence manipulation Grant US-9822372-B2 United States of America 21 Nov 2017
Engineering of systems, methods and optimized guide compositions for sequence manipulation Grant EP-2784162-B1 European Patent Office 08 Apr 2015