HERC6 Is the Main E3 Ligase for Global ISG15 Conjugation in Mouse Cells

Overview of attention for article published in PLOS ONE, January 2012

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HERC5 downregulation in non-small cell lung cancer is associated with altered energy metabolism and metastasis

Article in Journal of Experimental & Clinical Cancer Research (April 2024)

Porcine HERC6 acts as major E3 ligase for ISGylation and is auto-ISGylated for effective ISGylation in porcine

Article in Microbial Pathogenesis (March 2024)

HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity

Article in Cell Reports (February 2024)