High efficiency base editors comprising Gam Grant US-11932884-B2 United States of America 19 Mar 2024
Methods and compositions for simultaneous editing of both strands of a target double-strand… Grant US-11912985-B2 United States of America 27 Feb 2024
Editing of CCR2 receptor gene to protect against HIV infection Grant US-11820969-B2 United States of America 21 Nov 2023
Methods for sensitizing cancer cells to T cell-mediated killing by modulating molecular… Grant US-11820822-B2 United States of America 21 Nov 2023
Methods and compositions for prime editing nucleotide sequences Grant US-11795452-B2 United States of America 24 Oct 2023
Adenosine nucleobase editors and uses thereof Grant US-11702651-B2 United States of America 18 Jul 2023
Programmable CAS9-recombinase fusion proteins and uses thereof Grant US-11661590-B2 United States of America 30 May 2023
Methods and compositions for prime editing nucleotide sequences Grant US-11643652-B2 United States of America 09 May 2023
CAS9 proteins including ligand-dependent inteins Grant US-11578343-B2 United States of America 14 Feb 2023
Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and… Grant US-11560566-B2 United States of America 24 Jan 2023
Incorporation of unnatural amino acids into proteins using base editing Grant US-11542509-B2 United States of America 03 Jan 2023
Methods and compositions for prime editing nucleotide sequences Grant US-11447770-B1 United States of America 20 Sep 2022
CRISPR-related methods and compositions with governing gRNAS Grant US-11390887-B2 United States of America 19 Jul 2022
High efficiency base editors comprising Gam Grant US-11319532-B2 United States of America 03 May 2022
METHODS FOR ENGINEERING ALLOGENEIC AND IMMUNOSUPPRESSIVE RESISTANT T CELL FOR… Application EP-3964567-A1 European Patent Office 09 Mar 2022
Nucleobase editors comprising nucleic acid programmable DNA binding proteins Grant US-11268082-B2 United States of America 08 Mar 2022
Fusions of Cas9 domains and nucleic acid-editing domains Grant US-11053481-B2 United States of America 06 Jul 2021
Engineered transcription activator-like effector (TALE) domains and uses thereof Grant US-11046948-B2 United States of America 29 Jun 2021
REPEAT VARIABLE DIRESIDUES FOR TARGETING NUCLEOTIDES Application EP-3799878-A2 European Patent Office 07 Apr 2021
Adenosine nucleobase editors and uses thereof Grant US-10947530-B2 United States of America 16 Mar 2021
Editing of CCR5 receptor gene to protect against HIV infection Grant US-10745677-B2 United States of America 18 Aug 2020
CAS9 proteins including ligand-dependent inteins Grant US-10704062-B2 United States of America 07 Jul 2020
CRISPR-related methods and compositions with governing gRNAs Grant US-10640788-B2 United States of America 05 May 2020
Methods for identifying a target site of a CAS9 nuclease Grant US-10508298-B2 United States of America 17 Dec 2019
CD123 SPECIFIC CHIMERIC ANTIGEN RECEPTORS FOR CANCER IMMUNOTHERAPY Application EP-3569619-A1 European Patent Office 20 Nov 2019
METHODS OF TRANSCRIPTION ACTIVATOR LIKE EFFECTOR ASSEMBLY Application EP-3461896-A3 European Patent Office 26 Jun 2019
Evaluation and improvement of nuclease cleavage specificity Grant US-10323236-B2 United States of America 18 Jun 2019
Methods of transcription activator like effector assembly Grant US-10273271-B2 United States of America 30 Apr 2019
METHODS FOR ENGINEERING ALLOGENEIC AND IMMUNOSUPPRESSIVE RESISTANT T CELL FOR… Application EP-3473707-A1 European Patent Office 24 Apr 2019
IMPROVED ANTI-CD123 CAR IN UNIVERSAL ENGINEERED IMMUNE T CELLS Application WO-2019072824-A1 World Intellectual Property Organisation (WIPO) 18 Apr 2019
Engineered transcription activator-like effector (TALE) domains and uses thereof Application US-10227581-B2 United States of America 12 Mar 2019
CRISPR-related methods and compositions with governing gRNAS Grant US-10190137-B2 United States of America 29 Jan 2019
COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING RADIATION-INDUCED BYSTANDER EFFECTS… Application WO-2019018451-A2 World Intellectual Property Organisation (WIPO) 24 Jan 2019
ANTI-HBV COMBINATION THERAPIES INVOLVING SPECIFIC ENDONUCLEASES Application WO-2018234239-A1 World Intellectual Property Organisation (WIPO) 27 Dec 2018
REPEAT VARIABLE DIRESIDUES FOR TARGETING NUCLEOTIDES Application EP-3415158-A2 European Patent Office 19 Dec 2018
Adenosine nucleobase editors and uses thereof Grant US-10113163-B2 United States of America 30 Oct 2018
CAS9 proteins including ligand-dependent inteins Grant US-10077453-B2 United States of America 18 Sep 2018
USE OF PRE T ALPHA OR FUNCTIONAL VARIANT THEREOF FOR EXPANDING TCR ALPHA DEFICIENT T CELLS Application EP-3279315-A2 European Patent Office 07 Feb 2018
CRISPR-related methods and compositions with governing gRNAS Grant US-9834791-B2 United States of America 05 Dec 2017
A METHOD OF ENGINEERING PRODRUG-SPECIFIC HYPERSENSITIVE T-CELLS FOR IMMUNOTHERAPY BY GENE… Application WO-2017178586-A1 World Intellectual Property Organisation (WIPO) 19 Oct 2017
MICELLE BASED SYSTEM NUCLEASE ENCAPSULATION FOR IN-VIVO GENE EDITING Application WO-2017144630-A1 World Intellectual Property Organisation (WIPO) 31 Aug 2017
REPEAT VARIABLE DIRESIDUES FOR TARGETING NUCLEOTIDES Application EP-3141259-A2 European Patent Office 15 Mar 2017
TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR ASSEMBLY Application EP-3118319-A1 European Patent Office 18 Jan 2017
ANTI-HSP70 SPECIFIC CHIMERIC ANTIGEN RECEPTORS (CARS) FOR CANCER IMMUNOTHERAPY Application WO-2016120217-A1 World Intellectual Property Organisation (WIPO) 04 Aug 2016
Engineered transcription activator-like effector (TALE) domains and uses thereof Grant US-9359599-B2 United States of America 07 Jun 2016
Evaluation and improvement of nuclease cleavage specificity Grant US-9322006-B2 United States of America 26 Apr 2016
Methods for identifying a target site of a Cas9 nuclease Grant US-9163284-B2 United States of America 20 Oct 2015
METHODS OF TRANSCRIPTION ACTIVATOR LIKE EFFECTOR ASSEMBLY Application EP-2732038-A4 European Patent Office 29 Jul 2015
Methods for correcting presenilin point mutations Application US-9068179-B1 United States of America 30 Jun 2015
GENOME ENGINEERING Application WO-2015013583-A2 World Intellectual Property Organisation (WIPO) 29 Jan 2015
IMPROVED POLYNUCLEOTIDE SEQUENCES ENCODING TALE REPEATS Application WO-2014198911-A1 World Intellectual Property Organisation (WIPO) 18 Dec 2014
METHODS FOR ENGINEERING HIGHLY ACTIVE T CELL FOR IMMUNOTHERAPY Application WO-2014184744-A1 World Intellectual Property Organisation (WIPO) 20 Nov 2014
METHODS FOR ENGINEERING ALLOGENEIC AND HIGHLY ACTIVE T CELL FOR IMMUNOTHERAPHY Application WO-2014184741-A1 World Intellectual Property Organisation (WIPO) 20 Nov 2014
TAL-EFFECTOR ASSEMBLY PLATFORM, CUSTOMIZED SERVICES, KITS AND ASSAYS Application WO-2013152220-A3 World Intellectual Property Organisation (WIPO) 20 Mar 2014
MULTI-CHAIN CHIMERIC ANTIGEN RECEPTOR AND USES THEREOF Application WO-2014039523-A1 World Intellectual Property Organisation (WIPO) 13 Mar 2014
NEW MODULAR BASE-SPECIFIC NUCLEIC ACID BINDING DOMAINS FROM BURKHOLDERIA RHIZOXINICA… Application WO-2014018601-A2 World Intellectual Property Organisation (WIPO) 30 Jan 2014
NEW TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR (TALE) FUSION PROTEIN Application WO-2013182910-A2 World Intellectual Property Organisation (WIPO) 12 Dec 2013
METHODS FOR ENGINEERING ALLOGENEIC AND IMMUNOSUPPRESSIVE RESISTANT T CELL FOR… Application WO-2013176915-A1 World Intellectual Property Organisation (WIPO) 28 Nov 2013
TAL-EFFECTOR ASSEMBLY PLATFORM, CUSTOMIZED SERVICES, KITS AND ASSAYS Application WO-2013152220-A2 World Intellectual Property Organisation (WIPO) 10 Oct 2013