Survey of Activated FLT3 Signaling in Leukemia

Overview of attention for article published in PLOS ONE, April 2011

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N-(3-Methoxyphenyl)-6-(7-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl)pyridin-2-amine is an inhibitor of the FLT3-ITD and BCR-ABL pathways, and potently inhibits FLT3-ITD/D835Y and FLT3-ITD/F691L secondary mutants

Article in Bioorganic Chemistry (November 2023)

Proteomic and phosphoproteomic measurements enhance ability to predict ex vivo drug response in AML

Article in Clinical Proteomics (July 2022)

MCL-1 Inhibition Overcomes Anti-apoptotic Adaptation to Targeted Therapies in B-Cell Precursor Acute Lymphoblastic Leukemia

Article in Frontiers in Cell and Developmental Biology (September 2021)