The involvement of DXM’s unique agonism of sigma-1 receptors on it’s antidepressant effects. This could be big. User DextronautOmega, in the r/DXM subreddit, 13 Jan 2019
Involvement of Sigma-1 Receptors in the Antidepressant Effects of DXM. Important in its distinction from ketamine User DextronautOmega, in the r/DXM subreddit, 19 May 2017
Involvement of Sigma-1 Receptors in the Antidepressant-like Effects of Dextromethorphan User haikyogirl, in the DrugNerds subreddit, 08 Apr 2014