Title |
Hypertrophy Dependent Doubling of L-Cells in Roux-en-Y Gastric Bypass Operated Rats
|
---|---|
Published in |
PLOS ONE, June 2013
|
DOI | 10.1371/journal.pone.0065696 |
Pubmed ID | |
Authors |
Carl Frederik Hansen, Marco Bueter, Nadine Theis, Thomas Lutz, Sarah Paulsen, Louise S. Dalbøge, Niels Vrang, Jacob Jelsing |
Abstract |
Roux-en-Y gastric bypass (RYGB) leads to a rapid remission of type 2 diabetes mellitus (T2DM), but the underlying mode of action remains incompletely understood. L-cell derived gut hormones such as glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) are thought to play a central role in the anti-diabetic effects of RYGB; therefore, an improved understanding of intestinal endocrine L-cell adaptability is considered pivotal. |
Mendeley readers
The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 2% |
Unknown | 82 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 15 | 18% |
Researcher | 14 | 17% |
Student > Master | 11 | 13% |
Student > Bachelor | 9 | 11% |
Professor > Associate Professor | 5 | 6% |
Other | 13 | 15% |
Unknown | 17 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 23 | 27% |
Agricultural and Biological Sciences | 15 | 18% |
Biochemistry, Genetics and Molecular Biology | 10 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 6% |
Neuroscience | 3 | 4% |
Other | 9 | 11% |
Unknown | 19 | 23% |