| Title |
Plasma PCSK9 Levels Are Elevated with Acute Myocardial Infarction in Two Independent Retrospective Angiographic Studies
|
|---|---|
| Published in |
PLOS ONE, September 2014
|
| DOI | 10.1371/journal.pone.0106294 |
| Pubmed ID | |
| Authors |
Naif A. M. Almontashiri, Ragnar O. Vilmundarson, Nima Ghasemzadeh, Sonny Dandona, Robert Roberts, Arshed A. Quyyumi, Hsiao-Huei Chen, Alexandre F. R. Stewart |
| Abstract |
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a circulating protein that promotes degradation of the low density lipoprotein (LDL) receptor. Mutations that block PCSK9 secretion reduce LDL-cholesterol and the incidence of myocardial infarction (MI). However, it remains unclear whether elevated plasma PCSK9 associates with coronary atherosclerosis (CAD) or more directly with rupture of the plaque causing MI. |
X Demographics
The data shown below were collected from the profiles of 20 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Saudi Arabia | 4 | 20% |
| United States | 2 | 10% |
| Canada | 1 | 5% |
| Unknown | 13 | 65% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 16 | 80% |
| Scientists | 3 | 15% |
| Practitioners (doctors, other healthcare professionals) | 1 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 2% |
| Canada | 1 | 2% |
| Unknown | 55 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 19% |
| Student > Master | 6 | 11% |
| Student > Ph. D. Student | 6 | 11% |
| Student > Bachelor | 4 | 7% |
| Student > Doctoral Student | 4 | 7% |
| Other | 13 | 23% |
| Unknown | 13 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 20 | 35% |
| Biochemistry, Genetics and Molecular Biology | 11 | 19% |
| Nursing and Health Professions | 3 | 5% |
| Unspecified | 2 | 4% |
| Agricultural and Biological Sciences | 2 | 4% |
| Other | 4 | 7% |
| Unknown | 15 | 26% |