| Title |
Direct Evidence for the Presence of Human Milk Oligosaccharides in the Circulation of Breastfed Infants
|
|---|---|
| Published in |
PLOS ONE, July 2014
|
| DOI | 10.1371/journal.pone.0101692 |
| Pubmed ID | |
| Authors |
Karen C. Goehring, Adam D. Kennedy, Pedro A. Prieto, Rachael H. Buck |
| Abstract |
It has been hypothesized that human milk oligosaccharides (HMOs) confer systemic health benefits to breastfed infants; however, plausible mechanisms for some effects, such as systemic immunomodulation, require HMOs to access the bloodstream of the developing infant. While small concentrations of HMOs have been detected in the urine of breastfed infants there are no published studies of these oligosaccharides accessing the plasma compartment of breastfed infants. Here we determined the relative fractions of several ingested HMOs in infant urine and plasma. Plasma from formula-fed infants was used as a control. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Peru | 1 | 25% |
| United States | 1 | 25% |
| Germany | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 218 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 2 | <1% |
| Germany | 1 | <1% |
| Brunei Darussalam | 1 | <1% |
| Brazil | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 212 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 50 | 23% |
| Student > Ph. D. Student | 27 | 12% |
| Student > Bachelor | 24 | 11% |
| Student > Master | 20 | 9% |
| Other | 16 | 7% |
| Other | 37 | 17% |
| Unknown | 44 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 57 | 26% |
| Biochemistry, Genetics and Molecular Biology | 26 | 12% |
| Chemistry | 20 | 9% |
| Medicine and Dentistry | 19 | 9% |
| Nursing and Health Professions | 11 | 5% |
| Other | 33 | 15% |
| Unknown | 52 | 24% |