Title |
Noninvasive Image Texture Analysis Differentiates K-ras Mutation from Pan-Wildtype NSCLC and Is Prognostic
|
---|---|
Published in |
PLOS ONE, July 2014
|
DOI | 10.1371/journal.pone.0100244 |
Pubmed ID | |
Authors |
Glen J. Weiss, Balaji Ganeshan, Kenneth A. Miles, David H. Campbell, Philip Y. Cheung, Samuel Frank, Ronald L. Korn |
Abstract |
Non-invasive characterization of a tumor's molecular features could enhance treatment management. Quantitative computed tomography (CT) based texture analysis (QTA) has been used to derive tumor heterogeneity information, and the appearance of the tumors has been shown to relate to patient outcome in non-small cell lung cancer (NSCLC) and other cancers. In this study, we examined the potential of tumoral QTA to differentiate K-ras mutant from pan-wildtype tumors and its prognostic potential using baseline pre-treatment non-contrast CT imaging in NSCLC. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | <1% |
United States | 1 | <1% |
Unknown | 108 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 21 | 19% |
Student > Master | 17 | 15% |
Researcher | 13 | 12% |
Other | 11 | 10% |
Student > Doctoral Student | 10 | 9% |
Other | 18 | 16% |
Unknown | 20 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 52 | 47% |
Computer Science | 6 | 5% |
Engineering | 6 | 5% |
Physics and Astronomy | 4 | 4% |
Agricultural and Biological Sciences | 3 | 3% |
Other | 10 | 9% |
Unknown | 29 | 26% |