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Does PGE1 Vasodilator Prevent Orthopaedic Implant-Related Infection in Diabetes? Preliminary Results in a Mouse Model

Overview of attention for article published in PLOS ONE, April 2014
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Title
Does PGE1 Vasodilator Prevent Orthopaedic Implant-Related Infection in Diabetes? Preliminary Results in a Mouse Model
Published in
PLOS ONE, April 2014
DOI 10.1371/journal.pone.0094758
Pubmed ID
Authors

Arianna B. Lovati, Carlo L. Romanò, Lorenzo Monti, Christian Vassena, Sara Previdi, Lorenzo Drago

Abstract

Implant-related infections are characterized by bacterial colonization and biofilm formation on the prosthesis. Diabetes represents one of the risk factors that increase the chances of prosthetic infections because of related severe peripheral vascular disease. Vasodilatation can be a therapeutic option to overcome diabetic vascular damages and increase the local blood supply. In this study, the effect of a PGE₁ vasodilator on the incidence of surgical infections in diabetic mice was investigated.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 10%
Student > Bachelor 5 10%
Student > Doctoral Student 5 10%
Student > Postgraduate 4 8%
Student > Ph. D. Student 4 8%
Other 12 23%
Unknown 17 33%
Readers by discipline Count As %
Medicine and Dentistry 20 38%
Immunology and Microbiology 4 8%
Engineering 3 6%
Veterinary Science and Veterinary Medicine 3 6%
Biochemistry, Genetics and Molecular Biology 2 4%
Other 4 8%
Unknown 16 31%