| Title |
Human Adipose Tissue-Derived Stromal/Stem Cells Promote Migration and Early Metastasis of Triple Negative Breast Cancer Xenografts
|
|---|---|
| Published in |
PLOS ONE, February 2014
|
| DOI | 10.1371/journal.pone.0089595 |
| Pubmed ID | |
| Authors |
Brian G. Rowan, Jeffrey M. Gimble, Mei Sheng, Muralidharan Anbalagan, Ryan K. Jones, Trivia P. Frazier, Majdouline Asher, Eduardo A. Lacayo, Paul L. Friedlander, Robert Kutner, Ernest S. Chiu |
| Abstract |
Fat grafting is used to restore breast defects after surgical resection of breast tumors. Supplementing fat grafts with adipose tissue-derived stromal/stem cells (ASCs) is proposed to improve the regenerative/restorative ability of the graft and retention. However, long term safety for ASC grafting in proximity of residual breast cancer cells is unknown. The objective of this study was to determine the impact of human ASCs derived from abdominal lipoaspirates of three donors, on a human breast cancer model that exhibits early metastasis. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 128 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 3% |
| Mexico | 1 | <1% |
| China | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 121 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 23 | 18% |
| Researcher | 22 | 17% |
| Student > Doctoral Student | 15 | 12% |
| Student > Master | 15 | 12% |
| Student > Postgraduate | 10 | 8% |
| Other | 20 | 16% |
| Unknown | 23 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 37 | 29% |
| Biochemistry, Genetics and Molecular Biology | 24 | 19% |
| Agricultural and Biological Sciences | 23 | 18% |
| Engineering | 4 | 3% |
| Chemistry | 4 | 3% |
| Other | 5 | 4% |
| Unknown | 31 | 24% |