Title |
Ischaemic Strokes in Patients with Pulmonary Arteriovenous Malformations and Hereditary Hemorrhagic Telangiectasia: Associations with Iron Deficiency and Platelets
|
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Published in |
PLOS ONE, February 2014
|
DOI | 10.1371/journal.pone.0088812 |
Pubmed ID | |
Authors |
Claire L. Shovlin, Basel Chamali, Vatshalan Santhirapala, John A. Livesey, Gillian Angus, Richard Manning, Michael A. Laffan, John Meek, Hannah C. Tighe, James E. Jackson |
Abstract |
Pulmonary first pass filtration of particles marginally exceeding ∼7 µm (the size of a red blood cell) is used routinely in diagnostics, and allows cellular aggregates forming or entering the circulation in the preceding cardiac cycle to lodge safely in pulmonary capillaries/arterioles. Pulmonary arteriovenous malformations compromise capillary bed filtration, and are commonly associated with ischaemic stroke. Cohorts with CT-scan evident malformations associated with the highest contrast echocardiographic shunt grades are known to be at higher stroke risk. Our goal was to identify within this broad grouping, which patients were at higher risk of stroke. |
X Demographics
Geographical breakdown
Country | Count | As % |
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France | 1 | 17% |
United Kingdom | 1 | 17% |
Spain | 1 | 17% |
Australia | 1 | 17% |
Canada | 1 | 17% |
Unknown | 1 | 17% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 1% |
Greece | 1 | 1% |
Unknown | 70 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 11 | 15% |
Student > Master | 10 | 14% |
Student > Bachelor | 8 | 11% |
Researcher | 7 | 10% |
Student > Ph. D. Student | 6 | 8% |
Other | 12 | 17% |
Unknown | 18 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 56% |
Agricultural and Biological Sciences | 4 | 6% |
Biochemistry, Genetics and Molecular Biology | 3 | 4% |
Nursing and Health Professions | 2 | 3% |
Engineering | 2 | 3% |
Other | 4 | 6% |
Unknown | 17 | 24% |