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Dynamic Association with Donor Cell Filopodia and Lipid-Modification Are Essential Features of Wnt8a during Patterning of the Zebrafish Neuroectoderm

Overview of attention for article published in PLOS ONE, January 2014
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Title
Dynamic Association with Donor Cell Filopodia and Lipid-Modification Are Essential Features of Wnt8a during Patterning of the Zebrafish Neuroectoderm
Published in
PLOS ONE, January 2014
DOI 10.1371/journal.pone.0084922
Pubmed ID
Authors

Marta Luz, Stephanie Spannl-Müller, Günes Özhan, Birgit Kagermeier-Schenk, Muriel Rhinn, Gilbert Weidinger, Michael Brand

Abstract

Wnt proteins are conserved signaling molecules that regulate pattern formation during animal development. Many Wnt proteins are post-translationally modified by addition of lipid adducts. Wnt8a provides a crucial signal for patterning the anteroposterior axis of the developing neural plate in vertebrates. However, it is not clear how this protein propagates from its source, the blastoderm margin, to the target cells in the prospective neural plate, and how lipid-modifications might influence Wnt8a propagation and activity.

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Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 63 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 28%
Student > Master 11 17%
Researcher 10 16%
Student > Bachelor 5 8%
Student > Doctoral Student 4 6%
Other 9 14%
Unknown 7 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 39%
Biochemistry, Genetics and Molecular Biology 22 34%
Neuroscience 3 5%
Physics and Astronomy 2 3%
Mathematics 1 2%
Other 4 6%
Unknown 7 11%