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An Inflammation Based Score Can Optimize the Selection of Patients with Advanced Cancer Considered for Early Phase Clinical Trials

Overview of attention for article published in PLOS ONE, January 2014
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Title
An Inflammation Based Score Can Optimize the Selection of Patients with Advanced Cancer Considered for Early Phase Clinical Trials
Published in
PLOS ONE, January 2014
DOI 10.1371/journal.pone.0083279
Pubmed ID
Authors

David J. Pinato, Chara Stavraka, Michael J. Flynn, Martin D. Forster, Séan M. O'Cathail, Michael J. Seckl, Rebecca S. Kristeleit, David Olmos, Samantha J. Turnbull, Sarah P. Blagden

Abstract

Adequate organ function and good performance status (PS) are common eligibility criteria for phase I trials. As inflammation is pathogenic and prognostic in cancer we investigated the prognostic performance of inflammation-based indices including the neutrophil (NLR) and platelet to lymphocyte ratio (PLR).

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Unknown 42 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 28%
Student > Ph. D. Student 7 16%
Other 4 9%
Student > Doctoral Student 4 9%
Student > Master 3 7%
Other 8 19%
Unknown 5 12%
Readers by discipline Count As %
Medicine and Dentistry 20 47%
Agricultural and Biological Sciences 4 9%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Biochemistry, Genetics and Molecular Biology 2 5%
Nursing and Health Professions 2 5%
Other 4 9%
Unknown 8 19%