| Title |
Markers of T Cell Infiltration and Function Associate with Favorable Outcome in Vascularized High-Grade Serous Ovarian Carcinoma
|
|---|---|
| Published in |
PLOS ONE, December 2013
|
| DOI | 10.1371/journal.pone.0082406 |
| Pubmed ID | |
| Authors |
Katelin N. Townsend, Jaeline E. Spowart, Hassan Huwait, Sima Eshragh, Nathan R. West, Mary A. Elrick, Steve E. Kalloger, Michael Anglesio, Peter H. Watson, David G. Huntsman, Julian J. Lum |
| Abstract |
When T cells infiltrate the tumor environment they encounter a myriad of metabolic stressors including hypoxia. Overcoming the limitations imposed by an inadequate tumor vasculature that contributes to these stressors may be a crucial step to immune cells mounting an effective anti-tumor response. We sought to determine whether the functional capacity of tumor infiltrating lymphocytes (TIL) could be influenced by the tumor vasculature and correlated this with survival in patients with ovarian cancer. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Pakistan | 1 | 2% |
| Unknown | 46 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 30% |
| Researcher | 8 | 17% |
| Student > Bachelor | 6 | 13% |
| Student > Master | 4 | 9% |
| Professor > Associate Professor | 3 | 6% |
| Other | 7 | 15% |
| Unknown | 5 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 18 | 38% |
| Immunology and Microbiology | 7 | 15% |
| Biochemistry, Genetics and Molecular Biology | 5 | 11% |
| Medicine and Dentistry | 5 | 11% |
| Psychology | 2 | 4% |
| Other | 3 | 6% |
| Unknown | 7 | 15% |