| Title |
The Zinc Transporter Zip5 (Slc39a5) Regulates Intestinal Zinc Excretion and Protects the Pancreas against Zinc Toxicity
|
|---|---|
| Published in |
PLOS ONE, November 2013
|
| DOI | 10.1371/journal.pone.0082149 |
| Pubmed ID | |
| Authors |
Jim Geiser, Robert C. De Lisle, Glen K. Andrews |
| Abstract |
ZIP5 localizes to the baso-lateral membranes of intestinal enterocytes and pancreatic acinar cells and is internalized and degraded coordinately in these cell-types during periods of dietary zinc deficiency. These cell-types are thought to control zinc excretion from the body. The baso-lateral localization and zinc-regulation of ZIP5 in these cells are unique among the 14 members of the Slc39a family and suggest that ZIP5 plays a role in zinc excretion. |
Mendeley readers
The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Spain | 1 | 2% |
| Sri Lanka | 1 | 2% |
| Singapore | 1 | 2% |
| Unknown | 54 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 24% |
| Student > Bachelor | 7 | 12% |
| Researcher | 6 | 10% |
| Student > Doctoral Student | 4 | 7% |
| Student > Postgraduate | 4 | 7% |
| Other | 10 | 17% |
| Unknown | 13 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 16 | 28% |
| Biochemistry, Genetics and Molecular Biology | 10 | 17% |
| Medicine and Dentistry | 6 | 10% |
| Chemistry | 5 | 9% |
| Nursing and Health Professions | 1 | 2% |
| Other | 6 | 10% |
| Unknown | 14 | 24% |