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A Machine Learned Classifier That Uses Gene Expression Data to Accurately Predict Estrogen Receptor Status

Overview of attention for article published in PLOS ONE, December 2013
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Title
A Machine Learned Classifier That Uses Gene Expression Data to Accurately Predict Estrogen Receptor Status
Published in
PLOS ONE, December 2013
DOI 10.1371/journal.pone.0082144
Pubmed ID
Authors

Meysam Bastani, Larissa Vos, Nasimeh Asgarian, Jean Deschenes, Kathryn Graham, John Mackey, Russell Greiner

Abstract

Selecting the appropriate treatment for breast cancer requires accurately determining the estrogen receptor (ER) status of the tumor. However, the standard for determining this status, immunohistochemical analysis of formalin-fixed paraffin embedded samples, suffers from numerous technical and reproducibility issues. Assessment of ER-status based on RNA expression can provide more objective, quantitative and reproducible test results.

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Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 2%
United States 1 2%
Unknown 59 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 16%
Other 6 10%
Student > Ph. D. Student 6 10%
Student > Bachelor 5 8%
Student > Master 4 7%
Other 15 25%
Unknown 15 25%
Readers by discipline Count As %
Medicine and Dentistry 15 25%
Computer Science 8 13%
Agricultural and Biological Sciences 6 10%
Engineering 6 10%
Biochemistry, Genetics and Molecular Biology 5 8%
Other 5 8%
Unknown 16 26%