Jason S. Haukoos, Jonathan D. Campbell, Amy A. Conroy, Emily Hopkins, Meggan M. Bucossi, Comilla Sasson, Alia A. Al-Tayyib, Mark W. Thrun, For the Denver ED HIV Opt-Out Study Group

The Centers for Disease Control and Prevention recommends nontargeted opt-out HIV screening in healthcare settings. Cost effectiveness is critical when considering potential screening methods. Our goal was to compare programmatic costs of nontargeted opt-out rapid HIV screening with physician-directed diagnostic rapid HIV testing in an urban emergency department (ED) as part of the Denver ED HIV Opt-Out Trial.