| Title |
Genetic Polymorphisms in Monoamine Systems and Outcome of Cognitive Behavior Therapy for Social Anxiety Disorder
|
|---|---|
| Published in |
PLOS ONE, November 2013
|
| DOI | 10.1371/journal.pone.0079015 |
| Pubmed ID | |
| Authors |
Evelyn Andersson, Christian Rück, Catharina Lavebratt, Erik Hedman, Martin Schalling, Nils Lindefors, Elias Eriksson, Per Carlbring, Gerhard Andersson, Tomas Furmark |
| Abstract |
The role of genetics for predicting the response to cognitive behavior therapy (CBT) for social anxiety disorder (SAD) has only been studied in one previous investigation. The serotonin transporter (5-HTTLPR), the catechol-o-methyltransferase (COMT) val158met, and the tryptophan hydroxylase-2 (TPH2) G-703T polymorphisms are implicated in the regulation of amygdala reactivity and fear extinction and therefore might be of relevance for CBT outcome. The aim of the present study was to investigate if these three gene variants predicted response to CBT in a large sample of SAD patients. |
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 20% |
| United States | 1 | 20% |
| Sweden | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 116 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Sweden | 1 | <1% |
| Portugal | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 112 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 29 | 25% |
| Student > Ph. D. Student | 18 | 16% |
| Student > Master | 15 | 13% |
| Student > Bachelor | 10 | 9% |
| Professor > Associate Professor | 5 | 4% |
| Other | 14 | 12% |
| Unknown | 25 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 47 | 41% |
| Medicine and Dentistry | 14 | 12% |
| Neuroscience | 13 | 11% |
| Agricultural and Biological Sciences | 5 | 4% |
| Biochemistry, Genetics and Molecular Biology | 3 | 3% |
| Other | 6 | 5% |
| Unknown | 28 | 24% |