Title |
Staphylococcal Superantigens Stimulate Immortalized Human Adipocytes to Produce Chemokines
|
---|---|
Published in |
PLOS ONE, October 2013
|
DOI | 10.1371/journal.pone.0077988 |
Pubmed ID | |
Authors |
Bao G. Vu, Francoise A. Gourronc, David A. Bernlohr, Patrick M. Schlievert, Aloysius J. Klingelhutz |
Abstract |
Human adipocytes may have significant functions in wound healing and the development of diabetes through production of pro-inflammatory cytokines after stimulation by gram-negative bacterial endotoxin. Diabetic foot ulcers are most often associated with staphylococcal infections. Adipocyte responses in the area of the wound may play a role in persistence and pathology. We studied the effect of staphylococcal superantigens (SAgs) on immortalized human adipocytes, alone and in the presence of bacterial endotoxin or staphylococcal α-toxin. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 60% |
United Kingdom | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 3 | 60% |
Members of the public | 2 | 40% |
Mendeley readers
The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 1 | 2% |
United States | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 40 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 19% |
Student > Ph. D. Student | 6 | 14% |
Student > Bachelor | 5 | 12% |
Lecturer | 4 | 9% |
Student > Master | 3 | 7% |
Other | 7 | 16% |
Unknown | 10 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 9 | 21% |
Medicine and Dentistry | 7 | 16% |
Immunology and Microbiology | 6 | 14% |
Biochemistry, Genetics and Molecular Biology | 3 | 7% |
Computer Science | 3 | 7% |
Other | 3 | 7% |
Unknown | 12 | 28% |