Title |
Synergistic Effect of Various Virulence Factors Leading to High Toxicity of Environmental V. cholerae Non-O1/ Non-O139 Isolates Lacking ctx Gene : Comparative Study with Clinical Strains
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Published in |
PLOS ONE, September 2013
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DOI | 10.1371/journal.pone.0076200 |
Pubmed ID | |
Authors |
Neha Rajpara, Kittappa Vinothkumar, Priyabrata Mohanty, Arun Kumar Singh, Rajesh Singh, Ritam Sinha, Dhrubajyoti Nag, Hemanta Koley, Ashima Kushwaha Bhardwaj |
Abstract |
Vibrio cholerae non-O1/ non-O139 serogroups have been reported to cause sporadic diarrhoea in humans. Cholera toxins have been mostly implicated for hypersecretion of ions and water into the small intestine. Though most of the V. cholerae non-O1/ non-O139 strains lack these cholera toxins, several other innate virulence factors contribute towards their pathogenicity. The environmental isolates may thus act as reservoirs for potential spreading of these virulence genes in the natural environment which may cause the emergence of epidemic-causing organisms. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 2% |
Unknown | 55 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 14% |
Student > Master | 8 | 14% |
Student > Ph. D. Student | 7 | 13% |
Student > Postgraduate | 6 | 11% |
Other | 3 | 5% |
Other | 9 | 16% |
Unknown | 15 | 27% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 11 | 20% |
Biochemistry, Genetics and Molecular Biology | 9 | 16% |
Environmental Science | 4 | 7% |
Medicine and Dentistry | 4 | 7% |
Nursing and Health Professions | 3 | 5% |
Other | 9 | 16% |
Unknown | 16 | 29% |