Title |
Mechanical Control of Organ Size in the Development of the Drosophila Wing Disc
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Published in |
PLOS ONE, October 2013
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DOI | 10.1371/journal.pone.0076171 |
Pubmed ID | |
Authors |
Thomas Schluck, Ulrike Nienhaus, Tinri Aegerter-Wilmsen, Christof M. Aegerter |
Abstract |
Control of cessation of growth in developing organs has recently been proposed to be influenced by mechanical forces acting on the tissue due to its growth. In particular, it was proposed that stretching of the tissue leads to an increase in cell proliferation. Using the model system of the Drosophila wing imaginal disc, we directly stretch the tissue finding a significant increase in cell proliferation, thus confirming this hypothesis. In addition, we characterize the growth over the entire growth period of the wing disc finding a correlation between the apical cell area and cell proliferation rate. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Canada | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
United Kingdom | 1 | 1% |
Germany | 1 | 1% |
Unknown | 84 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 32 | 36% |
Researcher | 16 | 18% |
Student > Master | 10 | 11% |
Student > Bachelor | 8 | 9% |
Professor > Associate Professor | 5 | 6% |
Other | 9 | 10% |
Unknown | 8 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 39 | 44% |
Biochemistry, Genetics and Molecular Biology | 26 | 30% |
Mathematics | 3 | 3% |
Chemical Engineering | 2 | 2% |
Neuroscience | 2 | 2% |
Other | 7 | 8% |
Unknown | 9 | 10% |