| Title |
Brain Docosahexaenoic Acid [DHA] Incorporation and Blood Flow Are Increased in Chronic Alcoholics: A Positron Emission Tomography Study Corrected for Cerebral Atrophy
|
|---|---|
| Published in |
PLOS ONE, October 2013
|
| DOI | 10.1371/journal.pone.0075333 |
| Pubmed ID | |
| Authors |
John C. Umhau, Weiyin Zhou, Shantalaxmi Thada, James Demar, Nahed Hussein, Abesh K. Bhattacharjee, Kaizong Ma, Sharon Majchrzak-Hong, Peter Herscovitch, Norman Salem, Abigail Urish, Joseph R. Hibbeln, Stephen C. Cunnane, Stanley I. Rapoport, Jussi Hirvonen |
| Abstract |
Chronic alcohol dependence has been associated with disturbed behavior, cerebral atrophy and a low plasma concentration of docosahexaenoic acid (DHA, 22∶6n-3), particularly if liver disease is present. In animal models, excessive alcohol consumption is reported to reduce brain DHA concentration, suggesting disturbed brain DHA metabolism. We hypothesized that brain DHA metabolism also is abnormal in chronic alcoholics. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 4% |
| Unknown | 26 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 4 | 15% |
| Student > Doctoral Student | 3 | 11% |
| Student > Ph. D. Student | 3 | 11% |
| Researcher | 2 | 7% |
| Other | 2 | 7% |
| Other | 3 | 11% |
| Unknown | 10 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 6 | 22% |
| Psychology | 3 | 11% |
| Medicine and Dentistry | 2 | 7% |
| Agricultural and Biological Sciences | 2 | 7% |
| Biochemistry, Genetics and Molecular Biology | 1 | 4% |
| Other | 2 | 7% |
| Unknown | 11 | 41% |