| Title |
Long-Term Effects of Statin Treatment in Elderly People: Extended Follow-Up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER)
|
|---|---|
| Published in |
PLOS ONE, September 2013
|
| DOI | 10.1371/journal.pone.0072642 |
| Pubmed ID | |
| Authors |
Suzanne M. Lloyd, David J. Stott, Anton J. M. de Craen, Patricia M. Kearney, Naveed Sattar, Ivan Perry, Christopher J. Packard, Andrew Briggs, Laura Marchbank, Harry Comber, J. Wouter Jukema, Rudi G. J. Westendorp, Stella Trompet, Brendan M. Buckley, Ian Ford |
| Abstract |
The PROspective Study of Pravastatin in the Elderly at Risk (PROSPER), a placebo-controlled trial of pravastatin, demonstrated a 19% reduction in coronary outcomes (p=0.006) after a mean of 3.2 years, with no impact on stroke outcomes or all-cause mortality. However, there was a suggestion of increased cancer risk. Our aim is to determine the long-term benefits and safety of pravastatin treatment in older people using post-trial follow-up of the PROSPER participants. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 38% |
| Spain | 2 | 25% |
| Norway | 1 | 13% |
| Unknown | 2 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 6 | 75% |
| Members of the public | 2 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 1% |
| Netherlands | 1 | 1% |
| Unknown | 71 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 16% |
| Student > Ph. D. Student | 8 | 11% |
| Student > Master | 7 | 10% |
| Other | 7 | 10% |
| Student > Bachelor | 6 | 8% |
| Other | 16 | 22% |
| Unknown | 17 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 36 | 49% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
| Biochemistry, Genetics and Molecular Biology | 2 | 3% |
| Nursing and Health Professions | 2 | 3% |
| Economics, Econometrics and Finance | 2 | 3% |
| Other | 8 | 11% |
| Unknown | 20 | 27% |