Title |
Clinical Relevance of Gain-Of-Function Mutations of p53 in High-Grade Serous Ovarian Carcinoma
|
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Published in |
PLOS ONE, August 2013
|
DOI | 10.1371/journal.pone.0072609 |
Pubmed ID | |
Authors |
Hyo Jeong Kang, Sung-Min Chun, Kyu-Rae Kim, Insuk Sohn, Chang Ohk Sung |
Abstract |
Inactivation of TP53, which occurs predominantly by missense mutations in exons 4-9, is a major genetic alteration in a subset of human cancer. In spite of growing evidence that gain-of-function (GOF) mutations of p53 also have oncogenic activity, little is known about the clinical relevance of these mutations. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 1 | 1% |
India | 1 | 1% |
United Kingdom | 1 | 1% |
Canada | 1 | 1% |
United States | 1 | 1% |
Unknown | 87 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 17 | 18% |
Student > Bachelor | 13 | 14% |
Researcher | 11 | 12% |
Student > Master | 11 | 12% |
Other | 8 | 9% |
Other | 13 | 14% |
Unknown | 19 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 23 | 25% |
Agricultural and Biological Sciences | 20 | 22% |
Medicine and Dentistry | 16 | 17% |
Environmental Science | 2 | 2% |
Mathematics | 2 | 2% |
Other | 6 | 7% |
Unknown | 23 | 25% |