Title |
Genetic Variants on 3q21 and in the Sp8 Transcription Factor Gene (SP8) as Susceptibility Loci for Psychotic Disorders: A Genetic Association Study
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Published in |
PLOS ONE, August 2013
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DOI | 10.1371/journal.pone.0070964 |
Pubmed ID | |
Authors |
Kenji Kondo, Masashi Ikeda, Yusuke Kajio, Takeo Saito, Yoshimi Iwayama, Branko Aleksic, Kazuo Yamada, Tomoko Toyota, Eiji Hattori, Hiroshi Ujike, Toshiya Inada, Hiroshi Kunugi, Tadafumi Kato, Takeo Yoshikawa, Norio Ozaki, Nakao Iwata |
Abstract |
Recent genome-wide association studies (GWASs) investigating bipolar disorder (BD) have detected a number of susceptibility genes. These studies have also provided novel insight into shared genetic components between BD and schizophrenia (SCZ), two major psychotic disorders. To examine the replication of the risk variants for BD and the pleiotropic effect of the variants associated with BD, we conducted a genetic association study of single nucleotide polymorphisms (SNPs) that were selected based upon previous BD GWASs, which targeted psychotic disorders (BD and SCZ) in the Japanese population. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 31 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 7 | 23% |
Researcher | 6 | 19% |
Student > Master | 3 | 10% |
Student > Doctoral Student | 2 | 6% |
Student > Bachelor | 2 | 6% |
Other | 3 | 10% |
Unknown | 8 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 16% |
Agricultural and Biological Sciences | 4 | 13% |
Neuroscience | 4 | 13% |
Biochemistry, Genetics and Molecular Biology | 3 | 10% |
Psychology | 3 | 10% |
Other | 2 | 6% |
Unknown | 10 | 32% |