| Title |
Suppression of HBV by Tenofovir in HBV/HIV Coinfected Patients: A Systematic Review and Meta-Analysis
|
|---|---|
| Published in |
PLOS ONE, July 2013
|
| DOI | 10.1371/journal.pone.0068152 |
| Pubmed ID | |
| Authors |
Huw Price, David Dunn, Deenan Pillay, Firouze Bani-Sadr, Theodora de Vries-Sluijs, Mamta K. Jain, Noriyoshi Kuzushita, Stefan Mauss, Marina Núñez, Reto Nüesch, Marion Peters, Thomas Reiberger, Christoph Stephan, Lionel Tan, Richard Gilson |
| Abstract |
Hepatitis B coinfection is common in HIV-positive individuals and as antiretroviral therapy has made death due to AIDS less common, hepatitis has become increasingly important. Several drugs are available to treat hepatitis B. The most potent and the one with the lowest risk of resistance appears to be tenofovir (TDF). However there are several questions that remain unanswered regarding the use of TDF, including the proportion of patients that achieves suppression of HBV viral load and over what time, whether suppression is durable and whether prior treatment with other HBV-active drugs such as lamivudine, compromises the efficacy of TDF due to possible selection of resistant HBV strains. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| France | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 82 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 22 | 26% |
| Student > Master | 14 | 16% |
| Student > Bachelor | 8 | 9% |
| Other | 6 | 7% |
| Student > Ph. D. Student | 6 | 7% |
| Other | 16 | 19% |
| Unknown | 13 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 41 | 48% |
| Nursing and Health Professions | 5 | 6% |
| Immunology and Microbiology | 4 | 5% |
| Agricultural and Biological Sciences | 3 | 4% |
| Sports and Recreations | 3 | 4% |
| Other | 12 | 14% |
| Unknown | 17 | 20% |