| Title |
A Melanoma Brain Metastasis with a Donor-Patient Hybrid Genome following Bone Marrow Transplantation: First Evidence for Fusion in Human Cancer
|
|---|---|
| Published in |
PLOS ONE, June 2013
|
| DOI | 10.1371/journal.pone.0066731 |
| Pubmed ID | |
| Authors |
Rossitza Lazova, Greggory S. LaBerge, Eric Duvall, Nicole Spoelstra, Vincent Klump, Mario Sznol, Dennis Cooper, Richard A. Spritz, Joseph T. Chang, John M. Pawelek |
| Abstract |
Tumor cell fusion with motile bone marrow-derived cells (BMDCs) has long been posited as a mechanism for cancer metastasis. While there is much support for this from cell culture and animal studies, it has yet to be confirmed in human cancer, as tumor and marrow-derived cells from the same patient cannot be easily distinguished genetically. |
X Demographics
The data shown below were collected from the profiles of 19 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 37% |
| Spain | 1 | 5% |
| Thailand | 1 | 5% |
| France | 1 | 5% |
| Argentina | 1 | 5% |
| South Africa | 1 | 5% |
| Hong Kong | 1 | 5% |
| Italy | 1 | 5% |
| Unknown | 5 | 26% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 14 | 74% |
| Scientists | 3 | 16% |
| Science communicators (journalists, bloggers, editors) | 1 | 5% |
| Practitioners (doctors, other healthcare professionals) | 1 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 1% |
| India | 1 | 1% |
| United States | 1 | 1% |
| South Africa | 1 | 1% |
| Unknown | 79 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 18% |
| Researcher | 15 | 18% |
| Student > Bachelor | 11 | 13% |
| Professor | 6 | 7% |
| Student > Postgraduate | 6 | 7% |
| Other | 17 | 20% |
| Unknown | 13 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 21 | 25% |
| Biochemistry, Genetics and Molecular Biology | 16 | 19% |
| Medicine and Dentistry | 14 | 17% |
| Immunology and Microbiology | 2 | 2% |
| Physics and Astronomy | 2 | 2% |
| Other | 10 | 12% |
| Unknown | 18 | 22% |