Title |
Propensity Score Estimation to Address Calendar Time-Specific Channeling in Comparative Effectiveness Research of Second Generation Antipsychotics
|
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Published in |
PLOS ONE, May 2013
|
DOI | 10.1371/journal.pone.0063973 |
Pubmed ID | |
Authors |
Stacie B. Dusetzina, Christina D. Mack, Til Stürmer |
Abstract |
Channeling occurs when a medication and its potential comparators are selectively prescribed based on differences in underlying patient characteristics. Drug safety advisories can provide new information regarding the relative safety or effectiveness of a drug product which might increase selective prescribing. In particular, when reported adverse effects vary among drugs within a therapeutic class, clinicians may channel patients toward or away from a drug based on the patient's underlying risk for an adverse outcome. If channeling is not identified and appropriately managed it might lead to confounding in observational comparative effectiveness studies. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 4% |
Unknown | 27 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 5 | 18% |
Student > Doctoral Student | 4 | 14% |
Librarian | 3 | 11% |
Student > Bachelor | 3 | 11% |
Other | 3 | 11% |
Other | 7 | 25% |
Unknown | 3 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 32% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 25% |
Nursing and Health Professions | 2 | 7% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Decision Sciences | 1 | 4% |
Other | 3 | 11% |
Unknown | 5 | 18% |