Title |
Opposite Effective Connectivity in the Posterior Cingulate and Medial Prefrontal Cortex between First-Episode Schizophrenic Patients with Suicide Risk and Healthy Controls
|
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Published in |
PLOS ONE, May 2013
|
DOI | 10.1371/journal.pone.0063477 |
Pubmed ID | |
Authors |
Huiran Zhang, Xiaomei Wei, Haojuan Tao, Tumbwene E. Mwansisya, Weidan Pu, Zhong He, Aimin Hu, Lin Xu, Zhening Liu, Baoci Shan, Zhimin Xue |
Abstract |
The schizophrenic patients with high suicide risk are characterized by depression, better cognitive function, and prominent positive symptoms. However, the neurobiological basis of suicide attempts in schizophrenia is not clear. The suicide in schizophrenia is implicated in the defects in emotional process and decision-making, which are associated with prefrontal-cingulate circuit. In order to explore the possible neurobiological basis of suicide in schizophrenia, we investigated the correlation of prefrontal-cingulate circuit with suicide risk in schizophrenia via dynamic casual modelling. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Canada | 1 | <1% |
Unknown | 120 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 27 | 22% |
Researcher | 21 | 17% |
Student > Master | 16 | 13% |
Student > Bachelor | 12 | 10% |
Other | 6 | 5% |
Other | 21 | 17% |
Unknown | 19 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 38 | 31% |
Medicine and Dentistry | 20 | 16% |
Neuroscience | 16 | 13% |
Nursing and Health Professions | 3 | 2% |
Unspecified | 3 | 2% |
Other | 11 | 9% |
Unknown | 31 | 25% |