| Title |
A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic
|
|---|---|
| Published in |
PLOS ONE, May 2013
|
| DOI | 10.1371/journal.pone.0063221 |
| Pubmed ID | |
| Authors |
Aaron Mobley, Suzanne K. Linder, Russell Braeuer, Lee M. Ellis, Leonard Zwelling |
| Abstract |
The pharmaceutical and biotechnology industries depend on findings from academic investigators prior to initiating programs to develop new diagnostic and therapeutic agents to benefit cancer patients. The success of these programs depends on the validity of published findings. This validity, represented by the reproducibility of published findings, has come into question recently as investigators from companies have raised the issue of poor reproducibility of published results from academic laboratories. Furthermore, retraction rates in high impact journals are climbing. |
X Demographics
The data shown below were collected from the profiles of 126 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 28 | 22% |
| United States | 22 | 17% |
| United Kingdom | 6 | 5% |
| Canada | 4 | 3% |
| Australia | 2 | 2% |
| France | 1 | <1% |
| Austria | 1 | <1% |
| Spain | 1 | <1% |
| Sweden | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 59 | 47% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 94 | 75% |
| Scientists | 28 | 22% |
| Practitioners (doctors, other healthcare professionals) | 2 | 2% |
| Science communicators (journalists, bloggers, editors) | 2 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 205 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 2% |
| Germany | 3 | 1% |
| United Kingdom | 2 | <1% |
| Switzerland | 1 | <1% |
| Uruguay | 1 | <1% |
| Brazil | 1 | <1% |
| Czechia | 1 | <1% |
| Chile | 1 | <1% |
| Mexico | 1 | <1% |
| Other | 3 | 1% |
| Unknown | 186 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 49 | 24% |
| Student > Ph. D. Student | 38 | 19% |
| Other | 18 | 9% |
| Student > Master | 18 | 9% |
| Student > Bachelor | 17 | 8% |
| Other | 42 | 20% |
| Unknown | 23 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 44 | 21% |
| Medicine and Dentistry | 27 | 13% |
| Biochemistry, Genetics and Molecular Biology | 16 | 8% |
| Computer Science | 14 | 7% |
| Engineering | 12 | 6% |
| Other | 59 | 29% |
| Unknown | 33 | 16% |