| Title |
Expression of Regulatory Platelet MicroRNAs in Patients with Sickle Cell Disease
|
|---|---|
| Published in |
PLOS ONE, April 2013
|
| DOI | 10.1371/journal.pone.0060932 |
| Pubmed ID | |
| Authors |
Shilpa Jain, Maria G. Kapetanaki, Nalini Raghavachari, Kimberly Woodhouse, Guoying Yu, Suchitra Barge, Claudia Coronnello, Panayiotis V. Benos, Gregory J. Kato, Naftali Kaminski, Mark T. Gladwin |
| Abstract |
Increased platelet activation in sickle cell disease (SCD) contributes to a state of hypercoagulability and confers a risk of thromboembolic complications. The role for post-transcriptional regulation of the platelet transcriptome by microRNAs (miRNAs) in SCD has not been previously explored. This is the first study to determine whether platelets from SCD exhibit an altered miRNA expression profile. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 1 | 1% |
| Canada | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 68 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 15% |
| Researcher | 9 | 13% |
| Student > Master | 8 | 11% |
| Student > Bachelor | 6 | 8% |
| Student > Doctoral Student | 5 | 7% |
| Other | 13 | 18% |
| Unknown | 19 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 20 | 28% |
| Biochemistry, Genetics and Molecular Biology | 13 | 18% |
| Medicine and Dentistry | 10 | 14% |
| Engineering | 2 | 3% |
| Immunology and Microbiology | 2 | 3% |
| Other | 5 | 7% |
| Unknown | 19 | 27% |