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Efficacy of Anti-Interleukin-5 Therapy with Mepolizumab in Patients with Asthma: A Meta-Analysis of Randomized Placebo-Controlled Trials

Overview of attention for article published in PLOS ONE, March 2013
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Title
Efficacy of Anti-Interleukin-5 Therapy with Mepolizumab in Patients with Asthma: A Meta-Analysis of Randomized Placebo-Controlled Trials
Published in
PLOS ONE, March 2013
DOI 10.1371/journal.pone.0059872
Pubmed ID
Authors

Yao Liu, Song Zhang, Dao-wei Li, Shu-juan Jiang

Abstract

Interleukin (IL)-5 is believed to be a key cytokine in eosinophil inflammatory infiltration in asthma. Previous clinical trials have evaluated the efficacy and safety of mepolizumab, a monoclonal antibody against IL-5, in patients with asthma. However, most of these studies were small, the conclusions were inconsistent, and the precise effects are therefore debatable.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 116 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 <1%
United States 1 <1%
India 1 <1%
France 1 <1%
Unknown 112 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 21 18%
Student > Ph. D. Student 17 15%
Student > Master 13 11%
Student > Bachelor 13 11%
Student > Doctoral Student 8 7%
Other 25 22%
Unknown 19 16%
Readers by discipline Count As %
Medicine and Dentistry 56 48%
Agricultural and Biological Sciences 8 7%
Pharmacology, Toxicology and Pharmaceutical Science 7 6%
Biochemistry, Genetics and Molecular Biology 5 4%
Immunology and Microbiology 5 4%
Other 14 12%
Unknown 21 18%