Title |
Genetic Loci Associated with Alzheimer’s Disease and Cerebrospinal Fluid Biomarkers in a Finnish Case-Control Cohort
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Published in |
PLOS ONE, April 2013
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DOI | 10.1371/journal.pone.0059676 |
Pubmed ID | |
Authors |
Lyzel S. Elias-Sonnenschein, Seppo Helisalmi, Teemu Natunen, Anette Hall, Teemu Paajanen, Sanna-Kaisa Herukka, Marjo Laitinen, Anne M. Remes, Anne M. Koivisto, Kari M. Mattila, Terho Lehtimäki, Frans R. J. Verhey, Pieter Jelle Visser, Hilkka Soininen, Mikko Hiltunen |
Abstract |
To understand the relation between risk genes for Alzheimer's disease (AD) and their influence on biomarkers for AD, we examined the association of AD in the Finnish cohort with single nucleotide polymorphisms (SNPs) from top AlzGene loci, genome-wide association studies (GWAS), and candidate gene studies; and tested the correlation between these SNPs and AD markers Aβ(1-42), total tau (t-tau), and phosphorylated tau (p-tau) in cerebrospinal fluid (CSF). |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 1% |
Spain | 1 | 1% |
Unknown | 73 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 16 | 21% |
Student > Master | 15 | 20% |
Researcher | 11 | 15% |
Student > Bachelor | 6 | 8% |
Student > Doctoral Student | 3 | 4% |
Other | 9 | 12% |
Unknown | 15 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 23 | 31% |
Neuroscience | 12 | 16% |
Biochemistry, Genetics and Molecular Biology | 7 | 9% |
Medicine and Dentistry | 6 | 8% |
Psychology | 3 | 4% |
Other | 8 | 11% |
Unknown | 16 | 21% |