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Genetic Loci Associated with Alzheimer’s Disease and Cerebrospinal Fluid Biomarkers in a Finnish Case-Control Cohort

Overview of attention for article published in PLOS ONE, April 2013
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Title
Genetic Loci Associated with Alzheimer’s Disease and Cerebrospinal Fluid Biomarkers in a Finnish Case-Control Cohort
Published in
PLOS ONE, April 2013
DOI 10.1371/journal.pone.0059676
Pubmed ID
Authors

Lyzel S. Elias-Sonnenschein, Seppo Helisalmi, Teemu Natunen, Anette Hall, Teemu Paajanen, Sanna-Kaisa Herukka, Marjo Laitinen, Anne M. Remes, Anne M. Koivisto, Kari M. Mattila, Terho Lehtimäki, Frans R. J. Verhey, Pieter Jelle Visser, Hilkka Soininen, Mikko Hiltunen

Abstract

To understand the relation between risk genes for Alzheimer's disease (AD) and their influence on biomarkers for AD, we examined the association of AD in the Finnish cohort with single nucleotide polymorphisms (SNPs) from top AlzGene loci, genome-wide association studies (GWAS), and candidate gene studies; and tested the correlation between these SNPs and AD markers Aβ(1-42), total tau (t-tau), and phosphorylated tau (p-tau) in cerebrospinal fluid (CSF).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 1%
Spain 1 1%
Unknown 73 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 21%
Student > Master 15 20%
Researcher 11 15%
Student > Bachelor 6 8%
Student > Doctoral Student 3 4%
Other 9 12%
Unknown 15 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 31%
Neuroscience 12 16%
Biochemistry, Genetics and Molecular Biology 7 9%
Medicine and Dentistry 6 8%
Psychology 3 4%
Other 8 11%
Unknown 16 21%