Title |
A Metabolomic Analysis of Two Intravenous Lipid Emulsions in a Murine Model
|
---|---|
Published in |
PLOS ONE, April 2013
|
DOI | 10.1371/journal.pone.0059653 |
Pubmed ID | |
Authors |
Brian T. Kalish, Hau D. Le, Kathleen M. Gura, Bruce R. Bistrian, Mark Puder |
Abstract |
Parenteral nutrition (PN), including intravenous lipid administration, is a life-saving therapy but can be complicated by cholestasis and liver disease. The administration of intravenous soy bean oil (SO) has been associated with the development of liver disease, while the administration of intravenous fish oil (FO) has been associated with the resolution of liver disease. The biochemical mechanism of this differential effect is unclear. This study compares SO and FO lipid emulsions in a murine model of hepatic steatosis, one of the first hits in PN-associated liver disease. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 46 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 22% |
Student > Master | 7 | 15% |
Other | 5 | 11% |
Student > Ph. D. Student | 4 | 9% |
Student > Bachelor | 3 | 7% |
Other | 12 | 26% |
Unknown | 5 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 30% |
Agricultural and Biological Sciences | 8 | 17% |
Nursing and Health Professions | 4 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 9% |
Business, Management and Accounting | 2 | 4% |
Other | 6 | 13% |
Unknown | 8 | 17% |