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DNA Vaccine Delivered by a Needle-Free Injection Device Improves Potency of Priming for Antibody and CD8+ T-Cell Responses after rAd5 Boost in a Randomized Clinical Trial

Overview of attention for article published in PLOS ONE, April 2013
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Title
DNA Vaccine Delivered by a Needle-Free Injection Device Improves Potency of Priming for Antibody and CD8+ T-Cell Responses after rAd5 Boost in a Randomized Clinical Trial
Published in
PLOS ONE, April 2013
DOI 10.1371/journal.pone.0059340
Pubmed ID
Authors

Barney S. Graham, Mary E. Enama, Martha C. Nason, Ingelise J. Gordon, Sheila A. Peel, Julie E. Ledgerwood, Sarah A. Plummer, John R. Mascola, Robert T. Bailer, Mario Roederer, Richard A. Koup, Gary J. Nabel

Abstract

DNA vaccine immunogenicity has been limited by inefficient delivery. Needle-free delivery of DNA using a CO2-powered Biojector® device was compared to delivery by needle and syringe and evaluated for safety and immunogenicity.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Ireland 1 1%
Unknown 81 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 21%
Student > Master 13 16%
Student > Bachelor 13 16%
Student > Ph. D. Student 8 10%
Student > Doctoral Student 7 9%
Other 8 10%
Unknown 16 20%
Readers by discipline Count As %
Medicine and Dentistry 14 17%
Biochemistry, Genetics and Molecular Biology 12 15%
Agricultural and Biological Sciences 11 13%
Immunology and Microbiology 10 12%
Pharmacology, Toxicology and Pharmaceutical Science 5 6%
Other 13 16%
Unknown 17 21%