Title |
DNA Vaccine Delivered by a Needle-Free Injection Device Improves Potency of Priming for Antibody and CD8+ T-Cell Responses after rAd5 Boost in a Randomized Clinical Trial
|
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Published in |
PLOS ONE, April 2013
|
DOI | 10.1371/journal.pone.0059340 |
Pubmed ID | |
Authors |
Barney S. Graham, Mary E. Enama, Martha C. Nason, Ingelise J. Gordon, Sheila A. Peel, Julie E. Ledgerwood, Sarah A. Plummer, John R. Mascola, Robert T. Bailer, Mario Roederer, Richard A. Koup, Gary J. Nabel |
Abstract |
DNA vaccine immunogenicity has been limited by inefficient delivery. Needle-free delivery of DNA using a CO2-powered Biojector® device was compared to delivery by needle and syringe and evaluated for safety and immunogenicity. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Iceland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Ireland | 1 | 1% |
Unknown | 81 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 17 | 21% |
Student > Master | 13 | 16% |
Student > Bachelor | 13 | 16% |
Student > Ph. D. Student | 8 | 10% |
Student > Doctoral Student | 7 | 9% |
Other | 8 | 10% |
Unknown | 16 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 17% |
Biochemistry, Genetics and Molecular Biology | 12 | 15% |
Agricultural and Biological Sciences | 11 | 13% |
Immunology and Microbiology | 10 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 6% |
Other | 13 | 16% |
Unknown | 17 | 21% |