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Microstructural White Matter Changes, Not Hippocampal Atrophy, Detect Early Amnestic Mild Cognitive Impairment

Overview of attention for article published in PLOS ONE, March 2013
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Title
Microstructural White Matter Changes, Not Hippocampal Atrophy, Detect Early Amnestic Mild Cognitive Impairment
Published in
PLOS ONE, March 2013
DOI 10.1371/journal.pone.0058887
Pubmed ID
Authors

Lin Zhuang, Perminder S. Sachdev, Julian N. Trollor, Simone Reppermund, Nicole A. Kochan, Henry Brodaty, Wei Wen

Abstract

Alzheimer's disease (AD) is generally considered to be characterized by pathology in gray matter of the brain, but convergent evidence suggests that white matter degradation also plays a vital role in its pathogenesis. The evolution of white matter deterioration and its relationship with gray matter atrophy remains elusive in amnestic mild cognitive impairment (aMCI), a prodromal stage of AD.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 147 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
United Kingdom 1 <1%
Italy 1 <1%
Unknown 143 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 38 26%
Student > Master 21 14%
Researcher 20 14%
Student > Doctoral Student 12 8%
Student > Bachelor 10 7%
Other 26 18%
Unknown 20 14%
Readers by discipline Count As %
Neuroscience 34 23%
Psychology 31 21%
Medicine and Dentistry 24 16%
Agricultural and Biological Sciences 12 8%
Engineering 5 3%
Other 15 10%
Unknown 26 18%