| Title |
Safety and Immunogenicity of Heterologous Prime-Boost Immunisation with Plasmodium falciparum Malaria Candidate Vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in Healthy Gambian and Kenyan Adults
|
|---|---|
| Published in |
PLOS ONE, March 2013
|
| DOI | 10.1371/journal.pone.0057726 |
| Pubmed ID | |
| Authors |
Caroline Ogwang, Muhammed Afolabi, Domtila Kimani, Ya Jankey Jagne, Susanne H. Sheehy, Carly M. Bliss, Christopher J. A. Duncan, Katharine A. Collins, Miguel A. Garcia Knight, Eva Kimani, Nicholas A. Anagnostou, Eleanor Berrie, Sarah Moyle, Sarah C. Gilbert, Alexandra J. Spencer, Peninah Soipei, Jenny Mueller, Joseph Okebe, Stefano Colloca, Riccardo Cortese, Nicola K. Viebig, Rachel Roberts, Katherine Gantlett, Alison M. Lawrie, Alfredo Nicosia, Egeruan B. Imoukhuede, Philip Bejon, Britta C. Urban, Katie L. Flanagan, Katie J. Ewer, Roma Chilengi, Adrian V. S. Hill, Kalifa Bojang |
| Abstract |
Heterologous prime boost immunization with chimpanzee adenovirus 63 (ChAd63) and Modified vaccinia Virus Ankara (MVA) vectored vaccines is a strategy recently shown to be capable of inducing strong cell mediated responses against several antigens from the malaria parasite. ChAd63-MVA expressing the Plasmodium falciparum pre-erythrocytic antigen ME-TRAP (multiple epitope string with thrombospondin-related adhesion protein) is a leading malaria vaccine candidate, capable of inducing sterile protection in malaria naïve adults following controlled human malaria infection (CHMI). |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| South Africa | 1 | 33% |
| Netherlands | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 133 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 2% |
| Spain | 1 | <1% |
| Unknown | 130 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 26 | 20% |
| Researcher | 26 | 20% |
| Student > Master | 22 | 17% |
| Student > Bachelor | 12 | 9% |
| Student > Doctoral Student | 5 | 4% |
| Other | 22 | 17% |
| Unknown | 20 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 29 | 22% |
| Medicine and Dentistry | 25 | 19% |
| Immunology and Microbiology | 23 | 17% |
| Biochemistry, Genetics and Molecular Biology | 14 | 11% |
| Nursing and Health Professions | 4 | 3% |
| Other | 14 | 11% |
| Unknown | 24 | 18% |