| Title |
A Single CD4 Test with 250 Cells/Mm3 Threshold Predicts Viral Suppression in HIV-Infected Adults Failing First-Line Therapy by Clinical Criteria
|
|---|---|
| Published in |
PLOS ONE, February 2013
|
| DOI | 10.1371/journal.pone.0057580 |
| Pubmed ID | |
| Authors |
Charles F. Gilks, A. Sarah Walker, Paula Munderi, Cissy Kityo, Andrew Reid, Elly Katabira, Ruth L. Goodall, Heiner Grosskurth, Peter Mugyenyi, James Hakim, Diana M. Gibb |
| Abstract |
In low-income countries, viral load (VL) monitoring of antiretroviral therapy (ART) is rarely available in the public sector for HIV-infected adults or children. Using clinical failure alone to identify first-line ART failure and trigger regimen switch may result in unnecessary use of costly second-line therapy. Our objective was to identify CD4 threshold values to confirm clinically-determined ART failure when VL is unavailable. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 20% |
| Nigeria | 1 | 20% |
| United Kingdom | 1 | 20% |
| United States | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 65 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 15 | 23% |
| Researcher | 10 | 15% |
| Student > Bachelor | 8 | 12% |
| Student > Ph. D. Student | 7 | 11% |
| Student > Doctoral Student | 5 | 8% |
| Other | 13 | 20% |
| Unknown | 8 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 29 | 44% |
| Nursing and Health Professions | 6 | 9% |
| Social Sciences | 5 | 8% |
| Immunology and Microbiology | 4 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
| Other | 10 | 15% |
| Unknown | 10 | 15% |