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Warburg and Crabtree Effects in Premalignant Barrett's Esophagus Cell Lines with Active Mitochondria

Overview of attention for article published in PLOS ONE, February 2013
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Title
Warburg and Crabtree Effects in Premalignant Barrett's Esophagus Cell Lines with Active Mitochondria
Published in
PLOS ONE, February 2013
DOI 10.1371/journal.pone.0056884
Pubmed ID
Authors

Martin T. Suchorolski, Thomas G. Paulson, Carissa A. Sanchez, David Hockenbery, Brian J. Reid

Abstract

Increased glycolysis is a hallmark of cancer metabolism, yet relatively little is known about this phenotype at premalignant stages of progression. Periodic ischemia occurs in the premalignant condition Barrett's esophagus (BE) due to tissue damage from chronic acid-bile reflux and may select for early adaptations to hypoxia, including upregulation of glycolysis.

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Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
United States 1 3%
India 1 3%
Unknown 37 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 28%
Student > Ph. D. Student 9 23%
Student > Master 5 13%
Student > Bachelor 3 8%
Professor > Associate Professor 2 5%
Other 2 5%
Unknown 8 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 9 23%
Agricultural and Biological Sciences 9 23%
Medicine and Dentistry 9 23%
Chemistry 2 5%
Computer Science 1 3%
Other 3 8%
Unknown 7 18%