Title |
Warburg and Crabtree Effects in Premalignant Barrett's Esophagus Cell Lines with Active Mitochondria
|
---|---|
Published in |
PLOS ONE, February 2013
|
DOI | 10.1371/journal.pone.0056884 |
Pubmed ID | |
Authors |
Martin T. Suchorolski, Thomas G. Paulson, Carissa A. Sanchez, David Hockenbery, Brian J. Reid |
Abstract |
Increased glycolysis is a hallmark of cancer metabolism, yet relatively little is known about this phenotype at premalignant stages of progression. Periodic ischemia occurs in the premalignant condition Barrett's esophagus (BE) due to tissue damage from chronic acid-bile reflux and may select for early adaptations to hypoxia, including upregulation of glycolysis. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 40% |
Spain | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 60% |
Scientists | 2 | 40% |
Mendeley readers
The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 3% |
United States | 1 | 3% |
India | 1 | 3% |
Unknown | 37 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 28% |
Student > Ph. D. Student | 9 | 23% |
Student > Master | 5 | 13% |
Student > Bachelor | 3 | 8% |
Professor > Associate Professor | 2 | 5% |
Other | 2 | 5% |
Unknown | 8 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 9 | 23% |
Agricultural and Biological Sciences | 9 | 23% |
Medicine and Dentistry | 9 | 23% |
Chemistry | 2 | 5% |
Computer Science | 1 | 3% |
Other | 3 | 8% |
Unknown | 7 | 18% |