Title |
Safety and Immunogenicity of Neonatal Pneumococcal Conjugate Vaccination in Papua New Guinean Children: A Randomised Controlled Trial
|
---|---|
Published in |
PLOS ONE, February 2013
|
DOI | 10.1371/journal.pone.0056698 |
Pubmed ID | |
Authors |
William S. Pomat, Anita H. J. van den Biggelaar, Suparat Phuanukoonnon, Jacinta Francis, Peter Jacoby, Peter M. Siba, Michael P. Alpers, John C. Reeder, Patrick G. Holt, Peter C. Richmond, Deborah Lehmann |
Abstract |
Approximately 826,000 children, mostly young infants, die annually from invasive pneumococcal disease. A 6-10-14-week schedule of pneumococcal conjugate vaccine (PCV) is efficacious but neonatal PCV may provide earlier protection and better coverage. We conducted an open randomized controlled trial in Papua New Guinea to compare safety, immunogenicity and priming for memory of 7-valent PCV (PCV7) given in a 0-1-2-month (neonatal) schedule with that of the routine 1-2-3-month (infant) schedule. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Kenya | 1 | 1% |
Unknown | 71 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 13 | 18% |
Researcher | 10 | 14% |
Student > Ph. D. Student | 10 | 14% |
Student > Bachelor | 6 | 8% |
Other | 3 | 4% |
Other | 10 | 14% |
Unknown | 20 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 31% |
Agricultural and Biological Sciences | 7 | 10% |
Nursing and Health Professions | 6 | 8% |
Immunology and Microbiology | 4 | 6% |
Business, Management and Accounting | 1 | 1% |
Other | 9 | 13% |
Unknown | 23 | 32% |