| Title |
EGFR Gene Copy Number as a Prognostic Marker in Colorectal Cancer Patients Treated with Cetuximab or Panitumumab: A Systematic Review and Meta Analysis
|
|---|---|
| Published in |
PLOS ONE, February 2013
|
| DOI | 10.1371/journal.pone.0056205 |
| Pubmed ID | |
| Authors |
Zheng Jiang, Chunxiang Li, Fuyuan Li, Xishan Wang |
| Abstract |
The epidermal growth factor receptor (EGFR) gene copy number (GCN) has been previously demonstrated to correlate with the clinical outcome of colorectal cancer (CRC) treated with anti-EGFR monoclonal antibodies (mAbs), although it remains controversial. We conducted a systematic review and meta-analysis to assess EGFR GCN as a potential biomarker of survival for patients with advanced CRC receiving treatment with anti-EGFR mAbs. |
Mendeley readers
The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 3% |
| Indonesia | 1 | 1% |
| Brazil | 1 | 1% |
| France | 1 | 1% |
| South Africa | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 72 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 24% |
| Student > Ph. D. Student | 14 | 18% |
| Student > Bachelor | 7 | 9% |
| Other | 6 | 8% |
| Student > Master | 6 | 8% |
| Other | 14 | 18% |
| Unknown | 13 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 38% |
| Agricultural and Biological Sciences | 16 | 20% |
| Biochemistry, Genetics and Molecular Biology | 7 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 8% |
| Arts and Humanities | 1 | 1% |
| Other | 7 | 9% |
| Unknown | 12 | 15% |