| Title |
A Reliable Way to Detect Endogenous Murine β-Amyloid
|
|---|---|
| Published in |
PLOS ONE, February 2013
|
| DOI | 10.1371/journal.pone.0055647 |
| Pubmed ID | |
| Authors |
Andrew F. Teich, Mitesh Patel, Ottavio Arancio |
| Abstract |
Unraveling the normal physiologic role of β-amyloid is likely crucial to understanding the pathogenesis of Alzheimer's disease. However, progress on this question is currently limited by the high background of many ELISAs for murine β-amyloid. Here, we examine the background signal of several murine β-amyloid ELISAs, and conclude that the majority of the background is from non-APP derived proteins. Most importantly, we identify ELISAs that eliminate this background signal. |
Mendeley readers
The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 3 | 3% |
| Korea, Republic of | 1 | 1% |
| Spain | 1 | 1% |
| Belgium | 1 | 1% |
| Unknown | 88 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 27% |
| Student > Master | 16 | 17% |
| Researcher | 14 | 15% |
| Student > Bachelor | 9 | 10% |
| Professor > Associate Professor | 7 | 7% |
| Other | 16 | 17% |
| Unknown | 7 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 31 | 33% |
| Neuroscience | 23 | 24% |
| Biochemistry, Genetics and Molecular Biology | 15 | 16% |
| Medicine and Dentistry | 6 | 6% |
| Chemistry | 3 | 3% |
| Other | 7 | 7% |
| Unknown | 9 | 10% |