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Prevalence of Subthreshold Hypomania and Impact on Internal Validity of RCTs for Major Depressive Disorder: Results from a National Epidemiological Sample

Overview of attention for article published in PLOS ONE, February 2013
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Title
Prevalence of Subthreshold Hypomania and Impact on Internal Validity of RCTs for Major Depressive Disorder: Results from a National Epidemiological Sample
Published in
PLOS ONE, February 2013
DOI 10.1371/journal.pone.0055448
Pubmed ID
Authors

Nicolas Hoertel, Yann Le Strat, Frédéric Limosin, Caroline Dubertret, Philip Gorwood

Abstract

Growing evidence supports the validity of distinguishing major depressive disorder (MDD) plus a lifetime history of subthreshold hypomania (D(m)) from pure MDD in psychiatric classifications. The present study sought to estimate the proportion of individuals with D(m) that would have been included in RCTs for MDD using typical eligibility criteria, and examine the potential impact of including these participants on internal validity.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 2%
Unknown 43 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 23%
Student > Ph. D. Student 5 11%
Student > Doctoral Student 3 7%
Student > Bachelor 3 7%
Other 3 7%
Other 5 11%
Unknown 15 34%
Readers by discipline Count As %
Medicine and Dentistry 10 23%
Psychology 8 18%
Social Sciences 4 9%
Computer Science 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 2 5%
Unknown 18 41%