| Title |
Efficacy of a Marine Bacterial Nuclease against Biofilm Forming Microorganisms Isolated from Chronic Rhinosinusitis
|
|---|---|
| Published in |
PLOS ONE, February 2013
|
| DOI | 10.1371/journal.pone.0055339 |
| Pubmed ID | |
| Authors |
Robert C. Shields, Norehan Mokhtar, Michael Ford, Michael J. Hall, J. Grant Burgess, Mohamed Reda ElBadawey, Nicholas S. Jakubovics |
| Abstract |
The persistent colonization of paranasal sinus mucosa by microbial biofilms is a major factor in the pathogenesis of chronic rhinosinusitis (CRS). Control of microorganisms within biofilms is hampered by the presence of viscous extracellular polymers of host or microbial origin, including nucleic acids. The aim of this study was to investigate the role of extracellular DNA in biofilm formation by bacteria associated with CRS. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 20% |
| United Kingdom | 1 | 20% |
| Unknown | 3 | 60% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| United States | 1 | <1% |
| France | 1 | <1% |
| Italy | 1 | <1% |
| Unknown | 115 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 27 | 23% |
| Researcher | 23 | 19% |
| Student > Master | 14 | 12% |
| Student > Bachelor | 7 | 6% |
| Student > Doctoral Student | 6 | 5% |
| Other | 19 | 16% |
| Unknown | 23 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 34 | 29% |
| Medicine and Dentistry | 17 | 14% |
| Biochemistry, Genetics and Molecular Biology | 15 | 13% |
| Immunology and Microbiology | 10 | 8% |
| Environmental Science | 3 | 3% |
| Other | 15 | 13% |
| Unknown | 25 | 21% |