| Title |
Colonic Immune Stimulation by Targeted Oral Vaccine
|
|---|---|
| Published in |
PLOS ONE, January 2013
|
| DOI | 10.1371/journal.pone.0055143 |
| Pubmed ID | |
| Authors |
Mahesh Kathania, Mojgan Zadeh, Yaíma L. Lightfoot, Robert M. Roman, Bikash Sahay, Jeffrey R. Abbott, Mansour Mohamadzadeh |
| Abstract |
Currently, sufficient data exist to support the use of lactobacilli as candidates for the development of new oral targeted vaccines. To this end, we have previously shown that Lactobacillus gasseri expressing the protective antigen (PA) component of anthrax toxin genetically fused to a dendritic cell (DC)-binding peptide (DCpep) induced efficacious humoral and T cell-mediated immune responses against Bacillus anthracis Sterne challenge. |
Mendeley readers
The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 20 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 7 | 35% |
| Student > Master | 3 | 15% |
| Professor > Associate Professor | 2 | 10% |
| Student > Doctoral Student | 2 | 10% |
| Student > Bachelor | 1 | 5% |
| Other | 3 | 15% |
| Unknown | 2 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 7 | 35% |
| Veterinary Science and Veterinary Medicine | 2 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 10% |
| Biochemistry, Genetics and Molecular Biology | 2 | 10% |
| Immunology and Microbiology | 2 | 10% |
| Other | 2 | 10% |
| Unknown | 3 | 15% |