Report for: Experimental Pain and Opioid Analgesia in Volunteers at High Risk for Obstructive Sleep Apnea

Title	Experimental Pain and Opioid Analgesia in Volunteers at High Risk for Obstructive Sleep Apnea
Published in	PLOS ONE, January 2013
DOI	10.1371/journal.pone.0054807
Pubmed ID	23382975
Authors	Anthony G. Doufas, Lu Tian, Kevin A. Padrez, Puntarica Suwanprathes, James A. Cardell, Holden T. Maecker, Periklis Panousis
Abstract	Obstructive sleep apnea (OSA) is characterized by recurrent nocturnal hypoxia and sleep disruption. Sleep fragmentation caused hyperalgesia in volunteers, while nocturnal hypoxemia enhanced morphine analgesic potency in children with OSA. This evidence directly relates to surgical OSA patients who are at risk for airway compromise due to postoperative use of opioids. Using accepted experimental pain models, we characterized pain processing and opioid analgesia in male volunteers recruited based on their risk for OSA.

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Egypt	1	100%

Type	Count	As %
Practitioners (doctors, other healthcare professionals)	1	100%

Mendeley readers

The data shown below were compiled from readership statistics for 113 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Country	Count	As %
Unknown	113	100%

Readers by professional status	Count	As %
Researcher	18	16%
Student > Bachelor	14	12%
Student > Master	13	12%
Other	10	9%
Student > Ph. D. Student	8	7%
Other	20	18%
Unknown	30	27%

Readers by discipline	Count	As %
Medicine and Dentistry	53	47%
Nursing and Health Professions	9	8%
Psychology	7	6%
Biochemistry, Genetics and Molecular Biology	3	3%
Agricultural and Biological Sciences	2	2%
Other	5	4%
Unknown	34	30%

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